Wednesday, February 15, 2017

gene expression profile outlier analysis


1) Packages that makes parametric assumption - mostly for microarray gene expression data.

MOST, ZOPET, OPPAR, mCOPA, PPST, OS, ORT.

2) non- parametric

coGPS. From the first glance look very useful.

#1 - non parametric
#2 - allows integration of multiple data types like expression, methylation and copy number.
#3 - permutation based p-value (based on D. Ghosh's work)
#4 -  Both gene and patience wise outlier detection.